The startup ClosedLoop has created a platform of predictive models to help organizations improve patient care.

An important aspect of treating patients with conditions like diabetes and heart disease is helping them stay healthy outside of the hospital before they to return to the doctor’s office with further complications.

But reaching the most vulnerable patients at the right time often has more to do with probabilities than clinical assessments. Artificial intelligence (AI) has the potential to help clinicians tackle these types of problems, by analyzing large datasets to identify the patients that would benefit most from preventative measures. However, leveraging AI has often required health care organizations to hire their own data scientists or settle for one-size-fits-all solutions that aren’t optimized for their patients.

Now the startup ClosedLoop.ai is helping health care organizations tap into the power of AI with a flexible analytics solution that lets hospitals quickly plug their data into machine learning models and get actionable results.

The platform is being used to help hospitals determine which patients are most likely to miss appointments, acquire infections like sepsis, benefit from periodic check ups, and more. Health insurers, in turn, are using ClosedLoop to make population-level predictions around things like patient readmissions and the onset or progression of chronic diseases.

“We built a health care data science platform that can take in whatever data an organization has, quickly build models that are specific to [their patients], and deploy those models,” says ClosedLoop co-founder and Chief Technology Officer Dave DeCaprio ’94. “Being able to take somebody’s data the way it lives in their system and convert that into a model that can be readily used is still a problem that requires a lot of [health care] domain knowledge, and that’s a lot of what we bring to the table.”

In light of the COVID-19 pandemic, ClosedLoop has also created a model that helps organizations identify the most vulnerable people in their region and prepare for patient surges. The open source tool, called the C-19 Index, has been used to connect high-risk patients with local resources and helped health care systems create risk scores for tens of millions of people overall.

The index is just the latest way that ClosedLoop is accelerating the health care industry’s adoption of AI to improve patient health, a goal DeCaprio has worked toward for the better part of his career.

In March, ClosedLoop began exploring ways its platform could help hospitals prepare for and respond to COVID-19. The efforts culminated in a company hackathon over the weekend of March 16. By Monday, ClosedLoop had an open source model on GitHub that assigned COVID-19 risk scores to Medicare patients. By that Friday, it had been used to make predictions on more than 2 million patients.

Today, the model works with all patients, not just those on Medicare, and it has been used to assess the vulnerability of communities around the country. Care organizations have used the model to project patient surges and help individuals at the highest risk understand what they can do to prevent infection.

“Some of it is just reaching out to people who are socially isolated to see if there’s something they can do,” DeCaprio says. “Someone who is 85 years old and shut in may not know there’s a community based organization that will deliver them groceries.”

For DeCaprio, bringing the predictive power of AI to health care has been a rewarding, if humbling, experience.

“The magnitude of the problems are so large that no matter what impact you have, you don’t feel like you’ve moved the needle enough,” he says. “At the same time, every time an organization says, ‘This is the primary tool our care managers have been using to figure out who to reach out to,’ it feels great.”

Source: MIT News

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